Medications Linked to Depression Risk

Published on 4.27.25

  A recent study published in the Annals of Medicine found that certain medications, such as GLP1 receptor agonists like Wegovy and Ozempic, have been linked to disruptions in brain chemistry. Researchers discovered that these medications can affect dopamine signals in individuals with specific genetic variations, potentially leading to an increased risk of depression. The study used computer simulation software to analyze the interaction between GLP1 agonists and genes associated with dopamine signaling. This is a worrying finding, especially considering the widespread use of such medications for weight management and diabetes treatment. These medications can affect brain chemistry in individuals with specific genetic variations, potentially leading to increased risk of depression. The study's findings highlight the need for further research into the potential long-term effects of these medications on mental health.

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